It also applies to the mixed lineage kinase domain-like protein (MLKL), which is a multifunctional protein and not just an enforcer of necroptosis [106], and the copper transport protein solute carrier family 31 member 1 (SLC31A1), which shows increased expression in gliomas, but whose exact role in cuproptosis still needs to be investigated [132]. This evidence concerns the gene SLC31A1 and central nervous system cancer.