This is also supported by other studies demonstrating a significant correlation between poor outcome of glioma patients and the expression of caspases 4, 5, 6, and 8, confirming the prognostic importance also of those caspases involved in the “non-classical” pyroptosis pathway (caspases 4 and 5) [94,95,96,97]. This evidence concerns the gene CASP4 and glioma.