Quijada et al.’s work (2008) was the only study that depicted a lack of correlation of the TG/GHDL ratio with insulin sensitivity indexes like HOMA or QUICKI but demonstrated that a significant proportion of obese children, those with hypertension and those with MS, exhibited a TG/HDL-C ratio of 3.5 or higher [12]. The gene discussed is INS; the disease is Hypertension.