CD274 and triple-negative breast carcinoma: In triple-negative breast cancer (TNBC), Zhang et al. identified that B4GALT1 bound by RBMS1 at 3′-UTR stabilizes its mRNA and promotes the glycosylation of PD-L1 and it protects PD-L1 from being ubiquitinated and degraded by proteasome [14] (Figure 2).