The asthma (ID: ebi-a-GCST90018795, sample size: 449,500) and allergic rhinitis and IgE-mediated food allergy (ID: ebi-a-GCST90038664, sample size: 484,598, ID: ebi-a-GCST90018625, sample size: 169,716, respectively) datasets were obtained from the studies by Sakaue S et al., 2021 [24] and Dönertaş HM et al., 2021 [25], respectively. Here, IGHE is linked to asthma.