With redox balance, TGF-β inhibits the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6, stimulates IL-10 [91], allows the differentiation of fibroblasts into myofibroblasts to help cover wounds [114], inhibits the TGF-β/Smad pathway and consequently reduces fibrosis and keloids [111,112]. Here, IL10 is linked to keloid.