The study found that administering dietary anti-oxidants at a dosage of 900 mg per day for 4 weeks did not result in any significant alterations in the blood biomarkers of inflammation (e.g., IL-1, IL-6, and TNF-α) or the severity of the disease in patients with RA who were undergoing conventional medical therapies [131]. This evidence concerns the gene TNF and rheumatoid arthritis.