Even though [68Ga]Ga-PSMA-11 PET/CT demonstrated higher accuracy than CT in the detection of HCC (above all for metastasis) and was associated with a management change in about half the patient cohort, only two patients presented liver lesions with significant uptake on [68Ga]Ga-PSMA-11 PET scans to propose RLT since no other local or systemic treatment options were viable. This evidence concerns the gene FOLH1 and hepatocellular carcinoma.