We can further propose TGF-β to be among the DAMPs as the growth factor is stored in the extracellular matrix [20] and identified in lysates of the human squamous carcinoma cell lines HSC2 and TR146, of gingival fibroblasts, but also in the supernatant of demineralized bone matrix [21]; all preparations have caused a robust increase in IL11, a TGF-β target gene, in the gingival fibroblasts cells [22,23]. Here, TGFB1 is linked to squamous cell carcinoma.