Some indices associated with obesity and metabolic dysfunction proposed for the evaluation of patients with probable NAFLD include the triglyceride–glucose index (TyG index), triglyceride glucose–body mass index (TyG-BMI), triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL), alanine aminotransferase aspartate aminotransferase ratio (ALT/AST ratio) and hepatic steatosis index (HSI), among others [8]. The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.