APLN and Arrhythmogenic right ventricular dysplasia: The most significant enrichment was in the Calcium signaling pathway, Apelin signaling pathway, PI3K-Akt signaling pathway, Oxytocin signaling pathway, Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Chemokine signaling pathway, Circadian entrainment, ECM–receptor interaction, and GABAergic synapse (Figure 4).