Branched-chain amino acid catabolism, glucose-6-phosphate dehydrogenase deficiency, ribose-5-phosphate isomerase deficiency, transaldolase deficiency, the valproic acid metabolism pathway, and the valproic acid pathway were found to be significantly impacted (p < 0.05). This evidence concerns the gene RPIA and hyperinsulinemic hypoglycemia, familial, 4.