Miller et al. [65] studied biological indicators of dementia and found an interaction between PTSD and Factor TN, as well as between PTSD and glial fibrillary acidic protein, but not with APOE e4 or ATN biomarkers (amyloid-beta deposition (A), pathologic tau (T), neurodegeneration (N)). The gene discussed is APOE; the disease is post-traumatic stress disorder.