Of note, the expression of TGF-β and SerpinB3 has been related to the activation of the WNT/β-catenin pathway in both hepatocellular carcinoma (HCC) and colorectal cancers, associating with more aggressive tumors, with an earlier recurrence and a worse prognosis [32,33]. Here, TGFB1 is linked to hepatocellular carcinoma.