The Integrated Liver Inflammatory Score (ILIS) is an HCC-specific prognostic index built on 5 blood parameters (albumin, bilirubin, ALP, neutrophil count and AFP) calculated as follows: 0.057 × albumin (g/L) + 0.978 × log (Bilirubin, μmol/L) + 1.341 × log (ALP, IU/L) + 0.086 × neutrophil (109/L) + 0.301 × log (AFP, μg/L). This evidence concerns the gene ALB and hepatocellular carcinoma.