In comparison with the normal breast tissues, the most upregulated eight genes in BC tissues, with the corresponding fold-change, are shown in Figure 12c–j as follows: UB1 (4.05-folds), KIF20A (4.86-folds), CCNB2 (4.03-folds), NDC80 (5.79-folds), AURKB (2.98-folds), CDCA8 (4.57-folds), CENPA (3.51-folds), and TPX2 (3.94-folds). This evidence concerns the gene CDCA8 and breast cancer.