Guo L et al. analysed the expression of B7H4, B7H3, and PD-L1 in tissues ranging from chronic superficial gastritis and atrophic gastritis samples to low-grade intraepithelial neoplasia samples, high-grade intraepithelial neoplasia samples, and gastric adenocarcinoma [40]. This evidence concerns the gene CD274 and intraepithelial neoplasia.