Non-tumoral breast epithelial MCF10A cells, ER+ breast cancer MCF7 and T47D cells and TNBC breast cancer MDA-MB-231 and BT20 cells were transfected with siRNA E-Syt-1, siRNA E-Syt2 or scramble siRNA (siRNA A) as control. Here, ESR1 is linked to breast carcinoma.