This study, therefore, examines the relationship between the TRAF2 (rs867186), TAB2 (rs237025), and IKBKB (rs13278372) gene polymorphisms, TRAF2, TAB2, and IKBKB protein levels, and the Ki-67 labeling index and the clinical and morphological signs of PAs, as well as the relationship between their combinations and the manifestation of PAs. The gene discussed is IKBKB; the disease is gonorrhea.