Neurofibromatosis type 1 (NF1) is an autosomal-dominant genetic disorder caused by loss of expression of the neurofibromin (Nf1 gene product) tumor suppressor gene on chromosome 17 and subsequent dysregulation of RAS/mitogen-activated protein kinase (MAPK) signaling in Schwann cells (SCs) [1,2]. Here, WNK2 is linked to neurofibromatosis type 1.