FTH1 and Iron deficiency anemia: Ferritin, a cytoplasmic iron-storage protein complex consisting of ferritin heavy chain 1 (FTH1) and ferritin light chain light (FTL) isoforms, undergoes autophagic degradation within lysosomes in response to iron deficiency, a process termed ferritinophagy, which maintains iron metabolism and homeostasis [48].