Of interest, when levels of activation of these signaling molecules were compared between MCPs and a panel of NSCLC control lines, the H820 cell line (the other model harboring an EGFR oncogenic alteration -exon 19 deletion- and the T790M mutation in our panel), was the only other cell line that clustered with the resistant MCPs (Fig S7). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.