Similarly, rs71508903 (intron variant of ARID5B involved in rheumatoid arthritis, hypothyroidism and vitiligo), rs2304206 (5 prime UTR variant of BCL2L12, IRF3 involved in vitiligo), rs4409785 (intron variant of LNCRNA-IUR, FAM76B and involved in rheumatoid arthritis, multiple sclerosis, autoimmune thyroid disease, basal cell carcinoma, vitiligo), rs1043101, rs10768122 (3 prime UTR variant of SLC1A2 involved in vitiligo) are found to be depleted in AFR. This evidence concerns the gene IRF3 and rheumatoid arthritis.