Next, we verified these 6 genes through the TCGA database.We found that TOP2A, AURKA, CCNA2 were overexpressed and IGFBP5 was low expression in cervical cancer, but IVL was overexpressed in cervical cancer, which was contrary to the result of GEO dataset in Fig. 8 and KRT1 was no significant difference in cervical cancer tissue and normal tissue. The gene discussed is TOP2A; the disease is cervical cancer.