Consistent with these findings, the cellular EIF5, which was stabilized by LINC00894 in immortal cells (Figs. 4 and 5) and brain tissues (Fig. 3), exhibited protective effects against ischemia (Fig. 3), further demonstrating that EIF5-controlled translation would benefit cellular survival (Figs. 3 and 4). This evidence concerns the gene EIF5 and ischemia.