Taken together, these three cases implicate the lncRNA ENSG00000257522 in the regulation of FOXG1. Additionally, previous studies have reported several individuals with FOXG1 syndrome that harbor disruptions in this region, including a translocation in “Patient 1” that directly disrupts ENSG00000257522 (Mehrjouy et al. 2018). This evidence concerns the gene FOXG1 and FOXG1 disorder.