The differentially methylated bb-CpGs in the blood of Parkinson’s patients were mapped to genes associated with susceptibility or mechanistically associated with disease characteristics: NQO2, RAB7A, TBC1D16, ULK1, CD302, CALD1 and PRTN3. The NQO2 gene was suggested to be an important factor in Parkinson’s disease, and promoter polymorphisms were associated with disease susceptibility31,32. This evidence concerns the gene NQO2 and Parkinsonism.