The differentially methylated bb-CpGs in the blood of Parkinson’s patients were mapped to genes associated with susceptibility or mechanistically associated with disease characteristics: NQO2, RAB7A, TBC1D16, ULK1, CD302, CALD1 and PRTN3. The NQO2 gene was suggested to be an important factor in Parkinson’s disease, and promoter polymorphisms were associated with disease susceptibility31,32. The gene discussed is TBC1D16; the disease is Parkinsonism.