ABL nonreceptor tyrosine kinase, which was first identified as an oncogene product (e.g., BCR-ABL) generated by chromosomal translocation in chronic myelogenous leukemia (CML), is ubiquitously expressed in mammalian cells and is also known as cellular ABL (e.g., ABL1), which plays essential physiological roles in multiple biological processes, including cell proliferation [31, 32], differentiation [33], tumorigenesis [34], stress responses [35, 36], cell migration and adhesion [37]. The gene discussed is ABL1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.