TNFRSF12A and neoplasm: There was no significant difference in tumour growth between C26 Fn14 WT and C26 Fn14 KO tumours (tumour volume on day 13 (mm3 ± SD); C26 Fn14 WT, 554 ± 228, n = 9; C26 Fn14 KO, 629 ± 140, n = 5; P = 0.5206) (Fig. 3b).