These DMRs identified in the treatment responders vs non responders at T2 and T3 located at RNF39, ALOX12, DUSP22, DIP2C and HOXA4, MUC4 genes, were all previously related to treatment outcome and/or development of PTSD, see Table 6 [11, 26, 33]. The gene discussed is ALOX12; the disease is post-traumatic stress disorder.