CD8A and myeloid sarcoma: Flow cytometry confirmed substantially lower numbers of CD4+ T cells, CD8+ T cells, Th1 helper cells, and IL-17-secreting (Th17) helper cells, important disease drivers in MS and EAE21,22, in EAE brains and spinal cords at D16 after A13 administration (Fig. 1e and Supplementary Fig. 1a, b).