We further conducted ChIP sequencing analyses to evaluate the effect of C/EBP-β phosphorylation at Thr250 (mice) upon the ability of C/EBP-β and FoxO1 to bind to the promoter regions of the Cat and Mnsod genes during myocardial ischemia in vivo (Fig. 7d). This evidence concerns the gene SOD2 and myocardial ischemia.