Critically ill patients often develop hypoproteinemia, which can mask elevated AG levels.[18] Therefore, calculating the albumin-corrected AG reduces the effect of low albumin on the AG and can facilitate the determination of the type of acidosis in critically ill patients.[19] Recently, Jiang et al[20] published the results of a similar study, using the same database, and reported the albumin-corrected AG, for predicting in-hospital mortality among ICU patients with sepsis using propensity score-matched analyses, as well as the AG that was directly calculated. Here, ALB is linked to Sepsis.