There is an ongoing effort to understand the genetic connection between anti-GBM-associated disease and ANCA-associated vasculitis.[12] It has been presented a potential avenue for the generation of anti-GBM antibodies by ANCA.[12] Additionally, our patient exhibited a higher level of anti-GBM and anti-MPO antibodies but demonstrated pauci-immune pathological findings in the kidney tissue. This evidence concerns the gene MPO and vasculitis.