On the other hand, in the murine macrophage RAW264.7 cell line, the miR-124-3p levels were associated with decreased TNFα, IL-6, and IL-1β (Ma et al., 2014), while in the serum of RA patients, no significant correlation was found between miR-124-3p and IL-6, TNFα or IL-8 cytokine levels (Goldbergová et al., 2018). The gene discussed is CXCL8; the disease is rheumatoid arthritis.