Flow cytometry assays demonstrated that both the VNP‐NC and AISI‐pLuxI‐htrA strains increased the proportion of antitumor M1‐type tumor‐associated macrophages (TAMs) and decreased the proportion of pro‐tumor M2‐type TAMs (Figure 5F; Figure S9C, Supporting Information). The gene discussed is HTRA1; the disease is neoplasm.