The higher levels of serum liver enzymes observed in the two SHR rat groups compared with the basal levels (AST: 50–150 IU/L; ALT: 30–130 IU/L) could have been due to their genetic predisposition to hypertension, as a relationship between hypertension and elevated levels of serum liver enzymes has been reported [37,38]. Here, GPT is linked to Hypertension.