Notably, the DEGs from the M-C contrast were enriched for biological processes important for NAFLD, such as “cholesterol homeostasis” (ABCA1, GRAMD1B, INSIG1, LDLR, MYLIP, PCSK9, SREBF2, TMEM97) and “lipid metabolic process” (ACSL3, ACSL4, FADS1, FADS2, INSIG1, LDLR, LIPE, NAAA, and SCD; Table 2 and Table S4). The gene discussed is GRAMD1B; the disease is metabolic dysfunction-associated steatotic liver disease.