Even though there are no studies that directly relate BED to the proteins Taste Receptor Type 1 Member 2 (TAST1R2) and Taste Receptor Type 1 Member 3 (TAST1R3), which are expressed in the tongue and palate, their importance has been observed, as they are described to participate in the regulation of taste (specifically in the taste of sweet flavors), and recent studies about obesity have proposed that the increase in the consumption of sweet foods can be affected by allele G of rs120338082 of the TAST1R2 gene, which codes for a protein that increases the threshold of sweet flavors [67,68]. The gene discussed is TAS1R3; the disease is obesity due to melanocortin 4 receptor deficiency.