FAM215A and uterine cervix neoplasm: For example a, new indole alkaloid, sclerotiamide C (13), showed significant inhibitory activity against HeLa, A549, HepG2, and SMMC7721 cell lines, with IC50 values of 1.7 ± 0.1, 1.6 ± 0.1, 1.8 ± 0.1, and 1.5 ± 0.1 μM, respectively, and 13 could induce apoptosis in HeLa cells by arresting the cell cycle, activating ROS production, and regulating apoptosis-related proteins in the MAPK signaling pathway, suggesting that 13 is a potential lead for further development as an anti-cervical tumor agent.