A further investigation discovered that TMPRSS2 expression was also associated with tumor-infiltrating lymphocytes (TIL), which included activated eosinophils, macrophages, natural killer T-cells, myeloid-derived suppressor cells, memory B-cells, active B-cells, regulatory T-cells, T follicular helper cells, type 1 T helper cells, type 2 T helper cells, central memory CD4 T-cells, and effector memory CD8 T-cells. Here, CD8A is linked to neoplasm.