In particular, LSAMP-AS3/TUSC7 has been recognised as a potential tumour-suppressing gene that a wealth of data have implicated in many human cancers, including glioma, pancreatic ductal adenocarcinoma, osteosarcoma, oesophageal squamous cell carcinoma, and colorectal, gastric, and breast cancers [37,38]. Here, LSAMP is linked to osteosarcoma.