There was significant downregulation (p < 0.05) of ULK1, BECN1, ATG5, and MAP1LC3A mRNA for both KRAS-WT CRC and KRAS-mut CRC for all values except ATG5 in KRAS-WT which was not significant (Figure 3A–D). Here, ULK1 is linked to colorectal carcinoma.