METTL3 and obesity due to melanocortin 4 receptor deficiency: The hypomethylation displayed within the obesity group indicates that the normal physiological mechanisms in controlling adipogenesis may be disrupted; thus, the evaluation of adipogenesis-associated genes FTO, METTL3, and YTHDF1 was performed on the 29 samples, which included control samples (n = 14) and samples in the obesity group (n = 15).