Indeed, (a) DLBCL with a GCB-cell-like immunophenotype has been significantly correlated with increased apoptosis, high expression levels of the pro-apoptotic proteins Bax, Bak, and Bid, and low expression levels of the anti-apoptotic protein Bcl-xl; and (b) DLBCL with increased expression levels of the GC-associated markers i.e., BCL6 and CD10 proteins, has been significantly correlated with increased apoptosis and proliferation of tumor cells [8,9]. This evidence concerns the gene BCL6 and diffuse large B-cell lymphoma.