HYAL2 and hyperinsulinemic hypoglycemia, familial, 4: Additional findings in the mice that were not reported in the humans with HYAL2 deficiency included elevated serum HA, Wormian bones in the frontal suture, decreased mineralization of the craniofacial bones, cervical vertebral abnormalities, thrombocytopenia with anemia, missing kidney, and premature death [53,95,98].