NFKB1 and nasopharyngeal carcinoma: Studies conducted by Wu et al. reported that the nasopharyngeal carcinoma cell line secreted EVs loading the Epstein-Barr virus, EBV-encoded latent membrane protein 1 (LMP1) with the ability to educate primary fibroblasts into CAFs via the NF-κB pathway, and this EV-mediated modulatory activity was reverted when the authors knocked-down the p65 subunit [75].