CD24 and autosomal dominant polycystic kidney disease: Subsequently, in 2021, they generated kidney tubuloids using a distinct population of CD24+ renal epithelial cells possessing unique metabolic and gene regulatory programs, demonstrating that CD24+ cell-derived renal tubules can be utilized to establish an ADPKD model using multiplexed CRISPR-Cas9 gene editing, rapidly inducing cyst formation [60].