C9 and amyotrophic lateral sclerosis: Significant atrophy was identified in bilateral amygdala (L and R: C9+ALS < HC, C9-ALS > C9+ALS; R: C9-ALS < HC), basal forebrain (L and R: C9-ALS < HC; R: C9+ALS < HC), hypothalamus (L and R: C9+ALS < HC; C9-ALS > C9+ALS), nucleus accumbens (L and R: C9+ALS < HC; C9-ALS > C9+ALS), and subiculum (L: C9-ALS < HC, C9+ALS < HC; R: C9-ALS < HC) (Table 2).