We next analyzed the expression of the CD74 in normal and tumor tissues using the TCGA database (PanCancer Atlas) and the UALCAN (The University of Alabama at Birmingham Cancer Data Analysis Portal) database, and we observed that copy number, mRNA and protein level of CD74 are upregulated in breast cancer and breast invasive carcinoma (Supplementary Figure S3). The gene discussed is CD74; the disease is invasive breast carcinoma.