Interestingly, both NEX+ neurons and GFAP+ astrocytes in the peri‐infarct region exhibited elevated Swell1 expression compared to the undamaged side (Figure 1E,F), suggesting that neuronal and astrocytic SWELL1 channels may play an important role in the pathogenesis of ischemic stroke. The gene discussed is LRRC8A; the disease is ischemic stroke.